UNDERSTANDING mCRPC
Receiving the diagnosis of mCRPC can be devastating, and understandably, may raise a lot of questions. To help you and your loved ones feel more confident with your treatment choices, it’s helpful to learn about your condition and what you can expect on the road ahead.
Metastatic castration-resistant prostate cancer (mCRPC) is a type of advanced prostate cancer that is resistant to medical (eg, hormonal) or surgical treatments that lower testosterone and has spread to other parts of the body.
In other words, your prostate cancer has progressed on androgen deprivation therapy (ADT) and has spread to other parts of your body.
Androgen deprivation – A treatment to suppress or block the production or action of male hormones. (National Cancer Institute: NCI Dictionary of Cancer Terms. Bethesda, MD: National Cancer Institute. 2013. Available at www.cancer.gov/dictionary. Accessed 5/13/2016.)
Watch a video explaining “What is mCRPC”
Is There a Word or Term You Don’t Understand?
Use this glossary of common medical terms to help you understand your diagnosis and treatment options.
The Role Androgens Play
You may be aware that the male body naturally produces hormones called androgens. The most well-known androgen in men is testosterone.
For men with mCRPC, androgens play a role in fueling the tumor. While not the only source, androgen is produced primarily in the testes and some is also produced by the adrenal glands, which are located above the kidneys.
We know now that the tumor itself is also a source of androgen production. While there are other key factors that contribute to the disease, androgen is one such factor.
Reducing the production of androgen is key in helping you and your doctor manage your illness.
Find more information about advanced prostate cancer at My Prostate Cancer Roadmap.
The Role Androgens Play
You may be aware that the male body naturally produces hormones called androgens. The most well-known androgen in men is testosterone.
For men with mCRPC, androgens play a role in fueling the tumor. While not the only source, androgen is produced primarily in the testes and some is also produced by the adrenal glands, which are located above the kidneys.
We know now that the tumor itself is also a source of androgen production. While there are other key factors that contribute to the disease, androgen is one such factor.
Reducing the production of androgen is key in helping you and your doctor manage your illness.
Find more information about advanced prostate cancer at My Prostate Cancer Roadmap.
TESTES
The testes are 2 egg-shaped male reproductive organs located in the scrotum. They produce sperm and the male hormone, testosterone.
ANDROGEN
Androgens are hormones produced by the body that control the development and maintenance of masculine characteristics.
Prostate Tumor Tissue
Adrenal Glands
The adrenal glands are endocrine glands that sit at the top of the kidneys.
What do you need the most support with?
What do you need the most support with?
SELECTING TREATMENT
Learning about your treatment options can help you take a more active part in the choices made about your care.
Be sure to have conversations with your doctor about your goals—what you want to get from your treatment—and how you’re doing.
Tips for Talking to Your Doctor
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Prepare your questions ahead of time |
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Don’t be afraid to ask for the information you want |
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Bring someone with you to your appointment. They’ll help you keep track of the information your doctor gives you |
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Repeat back what your doctor tells you in your own words to make sure you’ve understood it |
Hear Al & Carol’s Story
“I try to make every day count.”
Hear perspectives on diagnosis from patients and caregivers.
FINDING THE HELP YOU NEED
Facing cancer can come with unexpected challenges. You may find you need help beyond what your healthcare provider and loved ones can offer.
When you need more support, consider reaching out to advocacy groups that can help connect you with services like legal and financial assistance, or to counseling and support groups for people facing similar challenges.
When caring for a loved one with cancer, it’s easy to overlook your own needs. Don’t hesitate to take time for yourself when you can, and reach out to friends and family for help.
Consider connecting with other caregivers, who may be able to offer guidance and share similar experiences.
