Frequently Asked Questions

What is ZYTIGA® (abiraterone acetate)?

ZYTIGA® is an oral, once-daily prescription medication used in combination with prednisone to treat men with metastatic castration-resistant prostate cancer (mCRPC)*. mCRPC is a prostate cancer that is resistant to medical (eg, hormonal) or surgical treatments that lower testosterone and has spread to other parts of the body.

*mCRPC is a type of advanced prostate cancer.

Learn more about ZYTIGA®

Who should not take ZYTIGA®?
  • Do not take ZYTIGA® if you are pregnant or may become pregnant. ZYTIGA® may harm your unborn baby.
  • Women who are pregnant or may become pregnant should not touch ZYTIGA® without protection, such as gloves.

Learn more about taking ZYTIGA®

What are the possible side effects of ZYTIGA®?

Oral, once-daily ZYTIGA® has an established safety profile. Learn more about side effects and important safety information and discuss taking ZYTIGA® with your doctor.

ZYTIGA® may cause serious side effects including:

  • High blood pressure (hypertension), low blood potassium levels (hypokalemia), and fluid retention (edema).

Tell your healthcare provider if you get any of the following symptoms:

    • Dizziness
    • Fast heartbeats
    • Feel faint or lightheaded
    • Headache
    • Confusion
    • Muscle weakness
    • Pain in your legs
    • Swelling in your legs or feet
  • Adrenal problems may happen if you stop taking prednisone, get an infection, or are under stress.
  • Liver problems. You may develop changes in liver function blood tests. Your healthcare provider will do blood tests to check your liver before treatment with ZYTIGA® and during treatment with ZYTIGA®. Liver failure may occur, which can lead to death. Tell your healthcare provider if you notice any of the following changes:
    • Yellowing of the skin or eyes
    • Darkening of the urine
    • Severe nausea or vomiting

The most common side effects of ZYTIGA® include:

    • Weakness
    • Joint swelling or pain
    • Swelling in your legs or feet
    • Hot flushes
    • Diarrhea
    • Vomiting
    • Cough
    • High blood pressure
    • Shortness of breath
    • Urinary tract infection
    • Bruising
    • Low red blood cells (anemia) and low blood potassium levels
    • High blood sugar levels, high blood cholesterol and triglycerides
    • Certain other abnormal blood tests

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.



How does ZYTIGA® work?

ZYTIGA® works by interrupting the androgen-making process at an important step. ZYTIGA® interrupts androgen production at three sources: the testes, the adrenal glands, AND the tumor itself.

Learn how ZYTIGA® works

ZYTIGA® may cause serious side effects including:

  • High blood pressure (hypertension), low blood potassium (hypokalemia), and fluid retention (edema).

Please see additional side effects and Important Safety Information.

How was ZYTIGA® proven effective?

ZYTIGA® was proven effective in two clinical trials—one for men with metastatic castration-resistant prostate cancer (mCRPC) who had not received prior chemotherapy and another for men with mCRPC who received prior chemotherapy containing docetaxel.

See the Clinical Trial Results

What support and resources are available to me during my treatment with ZYTIGA®?

You'll find that real people and personalized support are available to you through ZytigaOne® Support and your ZytigaOne® Support Care Coordinator.

Additionally, the ZytigaOne® Support Instant Savings Program is available to eligible patients with commercial insurance.

What role can ZytigaOne® Support Care Coordinators play in my treatment journey?

ZytigaOne® Support Care Coordinators are available as a convenient resource for services and information regarding ZYTIGA®.

What are the options to help cover the cost of my medication?

Paying for your treatment doesn't have to be complicated. ZytigaOne® Support can speak to you about several potential options for helping you manage your out-of-pocket costs for ZYTIGA®, whether you have commercial insurance, have government insurance, such as Medicare, or are uninsured.

What should I tell my healthcare provider before taking ZYTIGA®?
Before you take ZYTIGA®, tell your healthcare provider if you:
  • Have heart problems
  • Have liver problems
  • Have a history of adrenal problems
  • Have a history of pituitary problems
  • Have any other medical conditions
  • Plan to become pregnant (See "Who should not take ZYTIGA®?")
  • Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA® passes into your breast milk. You and your healthcare provider should decide if you will take ZYTIGA® and breastfeed. You should not do both. (See "Who should not take ZYTIGA®?")
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZYTIGA® can interact with many other medicines.

Learn more about talking to your Doctor

How should I take ZYTIGA®?

Take ZYTIGA® plus prednisone exactly as your healthcare provider tells you.

Learn more about taking ZYTIGA®

What should I do if I miss a daily dose of ZYTIGA®?

If you miss a dose of ZYTIGA® or prednisone, take your prescribed dose the following day. If you miss more than 1 dose, tell your healthcare provider right away.

Learn more about taking ZYTIGA®
Watch our video, “How to Take ZYTIGA®