Side Effects

What Are the Potential Side Effects of ZYTIGA®(abiraterone acetate)?

Oral, once-daily ZYTIGA® has an established safety profile. Please read the information about side effects and important safety information listed below.

It's always important to know the potential side effects of any medication you're taking or may start to take. These are not all the possible side effects of ZYTIGA®. For more information, ask your healthcare provider or pharmacist.

ZYTIGA® may cause serious side effects including:

  • High blood pressure (hypertension), low blood potassium (hypokalemia), and fluid retention (edema).

Tell your healthcare provider if you get any of the following symptoms:

    • Dizziness

    • Fast heartbeats

    • Feel faint or lightheaded

    • Headache

    • Confusion

    • Muscle weakness

    • Pain in your legs

    • Swelling in your legs or feet

  • Adrenal problems may happen if you stop taking prednisone, get an infection, or are under stress.

  • Liver problems. You may develop changes in liver function blood tests. Your healthcare provider will do blood tests to check your liver before treatment with ZYTIGA® and during treatment with ZYTIGA®. Liver failure may occur, which can lead to death. Tell your healthcare provider if you notice any of the following changes:

    • Yellowing of the skin or eyes
    • Darkening of the urine
    • Severe nausea or vomiting

The most common side effects of ZYTIGA® include:

    • Weakness

    • Joint swelling or pain

    • Swelling in your legs or feet

    • Hot flushes

    • Diarrhea

    • Vomiting

    • Cough

    • High blood pressure

    • Shortness of breath

    • Urinary tract infection

    • Bruising

    • Low red blood cells (anemia) and low blood potassium levels

    • High blood sugar levels, high blood cholesterol and triglycerides

    • Certain other abnormal blood tests

 

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®.

FOR MORE INFORMATION, ASK YOUR HEALTHCARE PROVIDER OR PHARMACIST.

Please see additional Important Safety Information below.