How ZYTIGA® (abiraterone acetate) Works

ZYTIGA® Inhibits Androgen Production at 3 Sources—Including the Tumor Itself

Oral, once-daily ZYTIGA® works by interrupting the androgen-making process at an important step. ZYTIGA® inhibits a key step in androgen production at three sources: the testesthe adrenal glands AND the tumor itself. Watch the following videos to learn How ZYTIGA® Works:

Chapter 1:
What is mCRPC?

Chapter 2:
Why ZYTIGA®?

Chapter 3:
Why Should I Ask My Doctor About ZYTIGA®?

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    How ZYTIGA® Works

    You may be aware that the male body naturally produces hormones called androgens . The most well known androgen in men is testosterone. For men with mCRPC, androgens play a role in fueling the tumor. While not the only source, androgen is produced primarily in the testes and some is also produced by the adrenal glands, which are located above the kidneys. We know now that the tumor itself is also a source of androgen production. While there are other key factors that contribute to the disease, androgen is one such factor.

    Reducing the production of androgen is key in helping you and your doctor manage your illness.

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    ZYTIGA® may cause serious side effects including:

    • High blood pressure (hypertension), low blood potassium levels (hypokalemia), and fluid retention (edema).

    Tell your healthcare provider if you get any of the following symptoms:

    • Dizziness

    • Fast heartbeats

    • Feel faint or lightheaded

    • Headache

    • Confusion

    • Muscle weakness

    • Pain in your legs

    • Swelling in your legs or feet

    Oral, once-daily ZYTIGA® works by interrupting the androgen-making process at an important step.

    Talk with your doctor to see if ZYTIGA® is right for you.