ZYTIGA® Inhibits Androgen Production at 3 Sources — Including the Tumor Itself
ZYTIGA® works by interrupting the androgen-making process at an important step. ZYTIGA® inhibits a key step in androgen production at three sources: the testes, the adrenal glands, AND the tumor itself.
The Role of Androgen in Metastatic Castration-Resistant
You may be aware that the male body naturally produces hormones called androgens. The most well known androgen in men is testosterone. While not the only source, androgen is produced primarily in the testes and some is also produced by the adrenal glands, which are
located above the kidneys. While there are
other key factors that contribute to the
disease, androgen is one such factor.
Research has shown that androgens help fuel the tumor. Reducing the production of androgen is key in helping you and your doctor manage your illness.
ZYTIGA® May Cause Serious Side Effects
ZYTIGA® has an established safety profile. Please read the information about side effects and important safety information listed below and discuss taking ZYTIGA® with your doctor.
ZYTIGA® may cause serious side effects including:
- High blood pressure (hypertension), low blood potassium levels (hypokalemia), and fluid retention (edema).
- Adrenal problems may happen if you stop taking prednisone, get an infection, or are under stress.
- Liver problems. You may develop changes in liver function blood test. Your healthcare provider will do blood tests to check your liver before treatment with ZYTIGA® and during treatment with ZYTIGA®.
Tell your healthcare provider if you get any of the following symptoms:
The most common side effects of ZYTIGA® include:
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®. FOR MORE INFORMATION, ASK YOUR HEALTHCARE PROVIDER OR PHARMACIST.