The Way Forward

If you're a caregiver or have a loved one with metastatic castration-resistant prostate cancer (prostate cancer that is resistant to medical [e.g. hormonal] or surgical treatments that lower testosterone and has spread to other parts of the body) you know how difficult this disease has been for him. You've helped your loved one through the ups and downs and have encouraged him to keep fighting. Now you may be wondering what the next step is.

ZYTIGA® Offers Another Option for Treatment

ZYTIGA® works by interrupting the androgen-making process at an important step.

ZYTIGA® inhibits androgen production at three sources: the testes, the adrenal glands, AND the tumor itself.

Research has shown that androgens help fuel the tumor. Reducing the production of androgen is key in helping you and your doctor manage your illness.

ZYTIGA® may cause serious side effects including:

  • Adrenal problems may happen if you stop taking prednisone, get an infection, or are under stress.
  • Liver problems. You may develop changes in liver function blood test. Your healthcare provider will do blood tests to check your liver before treatment with ZYTIGA® and during treatment with ZYTIGA®.

Encourage Your Loved One to Talk to His Doctor About ZYTIGA®

Your loved one may be reluctant to explore another therapy. His previous therapies may have been challenging. He needs to know about the effectiveness, possible side effects and expense of any treatments the doctor may be recommending. But you can help.

  • Talk with him about the benefits of ZYTIGA®.
  • Encourage your loved one to schedule an appointment with his oncologist or urologist specifically to ask if ZYTIGA® is right for him. Prepare for his doctor visit with our Doctor Discussion Guide.
  • Provide your loved one with information about ZYTIGA®, by showing him the information from this website and getting our free Prostate Cancer Information Kit.

When Your Loved One Is Being Treated with ZYTIGA®

You've been with your loved one every step of the way on this journey. You can help with this step in his treatment, as well.

Get the ZytigaOne™ Support Brochure
The brochure presents the many resources available from ZytigaOne™ Support.

What is ZYTIGA®?

ZYTIGA® (abiraterone acetate) is a prescription medicine that is used along with prednisone. ZYTIGA® is used to treat men with castration-resistant prostate cancer (prostate cancer that is resistant to medical or surgical treatments that lower testosterone) that has spread to other parts of the body.

IMPORTANT SAFETY INFORMATION

Who should not take ZYTIGA®(abiraterone acetate)?

Do not take ZYTIGA® if you are pregnant or may become pregnant. ZYTIGA® may harm your unborn baby. Women who are pregnant or who may become pregnant should not touch ZYTIGA® without protection, such as gloves.

ZYTIGA® is not for use in women or children. Keep ZYTIGA® and all medicines out of the reach of children.

Before you take ZYTIGA®, tell your healthcare provider if you:

  • Have heart problems
  • Have liver problems
  • Have a history of adrenal problems
  • Have a history of pituitary problems
  • Have any other medical conditions
  • Plan to become pregnant (See "Who should not take ZYTIGA®?")
  • Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA® passes into your breast milk. You and your healthcare provider should decide if you will take ZYTIGA® or breastfeed. You should not do both. (See "Who should not take ZYTIGA®?")
  • Take any other medicines, including prescription and non-prescription medicines, vitamins, and herbal supplements. ZYTIGA® can interact with many other medicines.

If you are taking ZYTIGA®:

  • Take ZYTIGA® and prednisone exactly as your healthcare provider tells you.
  • Take your prescribed dose of ZYTIGA® one time a day. Your healthcare provider may change your dose if needed.
  • Do not stop taking your prescribed dose of ZYTIGA® or prednisone without talking to your healthcare provider first.
  • Take ZYTIGA® on an empty stomach. Do not take ZYTIGA® with food. Taking ZYTIGA® with food may cause more of the medicine to be absorbed by the body than is needed and this may cause side effects.
  • No food should be eaten 2 hours before and 1 hour after taking ZYTIGA®.
  • Swallow ZYTIGA® tablets whole. Do not crush or chew tablets.
  • Take ZYTIGA® tablets with water.
  • Your healthcare provider will do blood tests to check for side effects.
  • Men who are sexually active with a pregnant woman must use a condom during and for one week after treatment with ZYTIGA®. If their sexual partner may become pregnant a condom and another form of birth control must be used during and for one week after treatment with ZYTIGA®. Talk with your healthcare provider if you have any questions about birth control.

ZYTIGA® may cause serious side effects including:

  • High blood pressure (hypertension), low blood potassium (hypokalemia), and fluid retention (edema).

    Tell your healthcare provider if you get any of the following symptoms:
    • Dizziness
    • Fast heartbeats
    • Feel faint or lightheaded
    • Headache
    • Confusion
    • Muscle weakness
    • Pain in your legs
    • Swelling in your legs or feet
  • Adrenal problems may happen if you stop taking prednisone, get an infection, or are under stress.
  • Liver problems. You may develop changes in liver function blood test. Your healthcare provider will do blood tests to check your liver before treatment with ZYTIGA® and during treatment with ZYTIGA®.
  • The most common side effects of ZYTIGA® include:
    • Weakness
    • Joint swelling or pain
    • Swelling in your legs or feet
    • Hot flushes
    • Diarrhea
    • Vomiting
    • Cough
    • High blood pressure
    • Shortness of breath
    • Urinary tract infection
    • Bruising
    • Low red blood cells (anemia) and low blood potassium levels
    • High blood sugar levels, high blood cholesterol and triglycerides
    • Certain other abnormal blood tests

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®.
FOR MORE INFORMATION, ASK YOUR HEALTHCARE PROVIDER OR PHARMACIST.

Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

ZYTIGA® can interact with many other medicines.

You should not start or stop any medicine before you talk with the healthcare provider who prescribed ZYTIGA®.

Know the medicines you take. Keep a list of them with you to show to your healthcare provider and pharmacist when you get a new medicine.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch, or call 1-800-FDA-1088 (1-800-332-1088).