During the course of the illness, prostate cancer may progress. It may become castration-resistant prostate cancer (CRPC), which is prostate cancer that has become resistant to medical or surgical treatments that lower testosterone. CRPC that spreads to other parts of the body is called metastatic castration-resistant prostate cancer (mCRPC).

Treatment Options

Many therapies are used to treat prostate cancer at its different stages. Not all treatments are appropriate for all patients at all stages of their disease. You may be familiar with certain treatment options, including:

The Role of Androgen

The male body produces male hormones called androgens. Research has shown that androgens help feed the tumor. Androgens, such as testosterone, are primarily made by your testes and your adrenal glands. However, in men with CRPC androgen is also made by an additional source — the tumor itself.

Research has shown that androgens help feed the tumor. Reducing the production of androgen is key to helping you and your doctor manage your illness because even a small amount of androgen may activate the tumor.

Related Information

Print our Brochure, “Discover ZYTIGA®”

If you or a loved one are considering ZYTIGA®, you can have important information at your fingertips.

What is ZYTIGA®?

ZYTIGA® (Zye-tee-ga) is a prescription medicine that is used along with prednisone. ZYTIGA® is used to treat men with castration-resistant prostate cancer (prostate cancer that is resistant to medical or surgical treatments that lower testosterone) that has spread to other parts of the body and who have previously received treatment with docetaxel.

Important Safety Information

Who should not take ZYTIGA®?

Do not take ZYTIGA® if you are pregnant or may become pregnant. ZYTIGA® may harm your unborn baby. Women who are pregnant or who may become pregnant should not touch ZYTIGA® without protection, such as gloves.

ZYTIGA® is not for use in women or children. Keep ZYTIGA® and all medicines out of the reach of children.

Before you take ZYTIGA®, tell your healthcare provider if you:

If you are taking ZYTIGA®:

ZYTIGA® may cause serious side effects including:

THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®.
FOR MORE INFORMATION, ASK YOUR HEALTHCARE PROVIDER OR PHARMACIST.

Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

ZYTIGA® can interact with other medicines.

You should not start or stop any medicine before you talk with the healthcare provider that prescribed ZYTIGA®.

Know the medicines you take. Keep a list of them with you to show to your healthcare provider and pharmacist when you get a new medicine.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch, or call 1-800-FDA-1088 (1-800-332-1088).